Glial dysfunction and persistent neuropathic postsurgical pain
نویسندگان
چکیده
منابع مشابه
Persistent postsurgical and posttrauma pain.
IT IS ESTIMATED that as many as 50% of patients who have undergone surgery experience persistent pain long after the expected postoperative recovery period, and in 2% to 10% of these individuals, the intensity of the pain is severe (see Table 1 for incidence associated with various surgical procedures). This type of pain is common in chronic pain centers, where as many as 20% of individuals see...
متن کاملPersistent postsurgical pain: risk factors and prevention.
Acute postoperative pain is followed by persistent pain in 10-50% of individuals after common operations, such as groin hernia repair, breast and thoracic surgery, leg amputation, and coronary artery bypass surgery. Since chronic pain can be severe in about 2-10% of these patients, persistent postsurgical pain represents a major, largely unrecognised clinical problem. Iatrogenic neuropathic pai...
متن کاملThe neuropathic component in persistent postsurgical pain: a systematic literature review.
Persistent postsurgical pain (PPSP) is a frequent and often disabling complication of many surgical procedures. Nerve injury-induced neuropathic pain (NeuP) has repeatedly been proposed as a major cause of PPSP. However, there is a lack of uniformity in NeuP assessment across studies, and the prevalence of NeuP may differ after various surgeries. We performed a systematic search of the PubMed, ...
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Chronic postsurgical pain (CPSP) is an important clinic problem. It is assessed that prevalence of chronic pain extends to 30% but it is contended that there are various risk factors. We aimed to evaluate the prevalence of chronic pain after hysterectomy, risk factors of chronicity, neuropathic features of pain, and sensorial alterations at surgery area.Between years 2012 and 2015, 16 to 65 age...
متن کاملNeural - Glial Interaction in Neuropathic Pain
Lesioning of the nervous system can produce a form of pathological pain called “neuropathic pain” that is characterized by sensory deficit, burning sensation, hyperalgesia and allodynia (Cui et al., 2000). The mechanisms underlying neuropathic pain have been studied extensively. Abundant evidence has indicated that aside from the neural component, the non-neural cells of the CNS, such as glial ...
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ژورنال
عنوان ژورنال: Scandinavian Journal of Pain
سال: 2016
ISSN: 1877-8879,1877-8860
DOI: 10.1016/j.sjpain.2015.10.002